Elfamed Inc
San Antonio, TX (USA)
Role(s):
Manager/Supervisor
Elfamed Inc.
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Startup
Location:
San Antonio
Industry:
Bio-Technology
Year Founded:
2004
Number Employees:
1-10 people
Business Stage:
Growth (profitable)
Entity Type:
"C" Corporation
Description:
HUMAN SCAR-FREE SKIN WOUND HEALING
Elfamed Inc. is a Biotechnology Regenerative Medicine company dedicated to the development of anti-scarring skin therapy by providing regenerative conditions to the skin stem cells located along the edge of the wound within the basal germinative cell layer.
Elfamed's innovative technology induces skin regeneration to minimize scar formation, restoring both function and aesthetic appearance.
Elfamed Inc. was funded by experts in primary cell culture. Initially the company focused in the development of an in-vitro anti-fibrotic process to purify human and animal primary cell cultures. Over the last 5 years the technology evolved from in-vitro to in-vivo applications.
Elfamed’s Regenerative patent pending technology uses cell culture proprietary technology, Proprietary Animal Protein-free cell culture media & Proprietary cell lines.
Scientific Platform
Prompt re-establishment of the basal germinative layer after wounding block off scarring.
To regenerate tissue it is noted you must eliminate the scar.
HUMAN PROOF-OF-CONCEPT
ELFAMED'S TECHNOLOGY REGENERATE FULL THICKNESS INCISIONAL AND EXCISIONAL HUMAN SKIN WOUNDS. ELFAMED'S INNOVATIVE REGENERATIVE TECHNOLOGY PROVIDES REGENERATIVE CONDITIONS BY LOCAL DOWNREGULATION OF PROINFLAMMATORY AND PROFIBROTIC FACTORS WITH A PROMPT AND ROBUST PROLIFERATION OF THE BASAL GERMINATIVE CELLS, TO RE-ESTABLISH THE BASAL GERMINATIVE CELL LAYER WHICH IS RESPONSIBLE FOR SKIN REGENERATION.
TECHNOLOGY
In wound healing, it is well documented that about three days after the wound occurs, fibroblasts begin to enter the wound site, marking the onset of the proliferative phase.
The scarring is created by fibroblast proliferation. Skin scars occur when the dermis is damaged.
Elfamed’s approach is to close the wound’s gap with its own basal germinative cells within those first three days, to regenerate skin by blocking off scarring.
Elfamed's technology regenerate full thickness incisional and excisional human skin wounds by locally down-regulating proinflammatory and profibrotic factors with a prompt and robust proliferation of the skin stem cells which are located in the basal germinative cell layer along the edge of the wound.
Regenerative conditions are set in place immediately after wounding. The prompt and robust proliferation of the skin stem cells close the gap of incisional and excisional human skin wounds blocking off scarring.
Elfamed's technology represents an important advance in the field of Regenerative Medicine, because shows how adult tissue can regenerate itself.
Elfamed's technology integrates 3 patents pending technologies in tissue engineering and regenerative medicine.
MARKET
Skin scarring is an enormous medical problem with approximately 100 million patients acquiring scars each year.
Scarring is a significant problem for regenerative medicine because the body’s typical response to a wound is to create scar tissue, which blocks the pathways of regeneration.
According to an independent market research group, the US commercial market for reduction of scarring in the skin is valued at approximately US$4 billion per year.
FACTS. Skin Wound Healing.
FACT: Superficial wounds heal scarless. The basal germinative cell layer is preserved.
FACT: Superficial skin wounds regenerate from the basal germinative cell layer of epidermis.
FACT: Skin Stem cells are located at the basal germinative cell layer of the epidermis.
FACT: Wounds that involve dermis heal with scar. The basal germinative cell layer has been disrupted and/or destroyed.
FACT: Scar (fibrosis) comes from fibroblasts, which are the most abundant cell type of the dermis.
A scar is collagen over expression that blocks off regeneration. In adult tissues there is a race between scarring and regeneration to which scarring usually wins by over expressing collagen.
About Elfamed:
Elfamed Inc. a Biotechnology Regenerative Medicine company is developing what can be the first human scarless skin wound healing technology in the market.
If you would like to learn more, please contact us at:
(Phone # removed)or
(URL removed)